References: Laxative





temp/constipation-16.matches:


Radiology. 1979 Feb;130(2):297-301.
The barium enema; evidence for proper utilization.

Gerson DE, Lewicki AM, McNeil BJ, Abrams HL, Korngold E.

A group of 1,041 patients was studied in an attempt to identify symptoms, signs, or laboratory findings (disease indicators) associated with either a high or low yield of abnormal barium enemas. A specific search was undertaken for subgroups with one or more statistically significant indicators of large bowel disease. If enemas were performed only for statistically significant indicators (fever, positive stool benzidine, rectal or abdominal mass, low hematocrit) or indicators of clinical importance (weight loss, constipation, diarrhea, etc.) only 13% of examinations would be eliminated. At the same time, however, 10% of patients with gastrointestinal disease would be missed.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=104358&dopt=Abstract

temp/constipation-10.matches:


Eur Surg Res. 1993;25(6):341-7.
Obturator internus muscle autotransplantation: a new concept for the treatment of obstructive constipation. An anatomical, physiological and pathological study.

Farag A, Gadallah NA, el-Shereif EM.

Department of General Surgery, Kasr El-Aini Hospital, Cairo University, Egypt.

The feasibility of using obturator internus muscle autotransplantation in order to construct an anal dilator mechanism for the treatment of obstructive constipation was studied anatomically, physiologically and pathologically. Electromyographic studies of 15 obturator internus muscles in 10 healthy adult male volunteers and 3 other muscles in patients with documented spastic anal sphincters demonstrated the ability of the obturator internus muscles to contract during straining at stools. The proposed surgical approach was studied in 9 cadavers (5 stillbirths and 4 adults), followed by formal anatomical dissection of the obturator internus muscle and tendon, pudendal nerve and vessels, inferior rectal nerve and nerve to the obturator internus. Anatomical studies proved the feasibility, ease, rapidity and safety of the technique with or without division of the obturator internus tendon with no incidence of injury to the surrounding nerves, vessels or muscles using a purely perineal approach.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8276032&dopt=Abstract

temp/constipation-16.matches:


Scand J Plast Reconstr Surg. 1979;13(1):193-4.
Successful use of a bulk laxative to control the diarrhea of tube feeding.

Frank HA, Green LC.

The greatly increased nutritional demands of the severely burned patient frequently require the use of tube feeding for enternal hyperalimentation. At a time when general patient morale is low and motivation needs to be maximally maintained, there is nothing so dispiriting as the distress of a painful perianal region and uncontrollable liquid stools. Attempts to control the diarrhea which frequently accompanies tube feeding by changing the formula or the method of administration or a wide variety of constipating drugs have all met with very limited success. Based on the clinical observation of a noted gastroenterologist (Bockus), we have administered a mucilagenous hydrophilic colloid bulk laxative (Metamucil) to patients on tube feeding formulae. The dosage and frequency are adjusted to individual patient needs, but average 7 g per liter of liquid formula. The results have been dramatic; namely, the virtual elimination of the diarrhea problem in our burn patients on enteral hyperalimentation by gastric tube feeding. Colonic transit time increases. The stools become formed but soft, cohesive but not adhesive. Perianal irritation does not occur. Neither does soilage of wound, dressings, or bed. No rebound constipation or obstructive symptoms have been encountered. We attribute this response to the same water binding mechanism that allows these colloids to prevent chronic constipation. Our patients may be given as much as 5,000 to 6,000 calories of tube feeding per day. Our patients are not distressed by diarrhea. Our nursing staff is relieved of the burden that entails.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=109911&dopt=Abstract



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